Motoric Clinical Symptoms in Late Onset Parkinson’s Disease at Dr. Hasan Sadikin General Hospital Bandung
Keywords:
Hoehn and Yarl scale, Hughes criteria, motoric clinical pattern, Parkinson’s diseaseAbstract
Background: Parkinson’s disease (PD) is a progressive neurological that disorder is characterized by a number of motoric symptoms which are resting tremor, bradykinesia, rigidity and postural disturbance. The main aim in carrying out this study was to observe the motoric clinical pattern in patients with late onset Parkinson’s disease based on age, gender, and staging of the disease.Methods: This was a descriptive retrospective study to 89 medical record of patients with late onset Parkinson’s disease from Neurology outpatient clinic of Dr. Hasan Sadikin General Hospital Bandung in the period January 2010 to January 2013. Total sampling was used to determine the population sample size The motoric clinical symptoms in patients with late onset Parkinson’s disease were classified based on age at diagnosis, gender, and staging of the disease conducted using descriptive retrospective method. Besides, staging was made based on Hoehn and Yarl scale.
Results: Overall, 92% of the patients with late onset Parkinson’s disease had resting tremor, and postural instability was less frequently found in 21% of patients. Sixty one men suffered from this disease, 43% were from the age group 60–69, and 32% were in stage III.
Conclusions: A majority of patients with the late onset Parkinson’s disease show resting tremor that has the common motoric clinical pattern, followed by bradykinesia, rigidity, and some show postural instability. [AMJ.2017;4(1):11–5]
DOI: 10.15850/amj.v4n1.1013
References
Martin W, Suchowersky O, Burns KK, Jonsson E, editors. Parkinson disease: a health policy perspective. Weinheim: Wiley VCH; 2010. [cited 2010 March 30]. Available from: http://onlinelibrary.wiley.com/book/10.1002/9783527629480
Fahn S. Description of parkinson’s disease as a clinical syndrome. Ann N Y Acad Sci. 2003;991(1):1−14.
Jankovic J, Tolosa E. Parkinson’s disease and movement disorders. 5th ed. Philadelphia, USA: Lippincott Williams & Wilkins; 2007.
Parkinson Disease Foundation. Understanding Parkinson’s: what causes Parkinson’s?. [cited 2014 September 20]: Available from: http://www.pdf.org/causes.
Pankratz N, Foroud T. Genetics of parkinson disease. NeuroRx. 2004;1(2):235−42.
Hindle JV. Ageing, neurodegeneration and parkinson’s disease. Age Ageing. 2010;39(2):156−61.
Levy G. The relationship of parkinson disease with aging. Arch Neurol. 2007;64(9):1242−6.
Dluzen DE. Unconventional effects of estrogen uncovered.Trends Pharmacol Sci. 2005;26(10):485−7.
Morissette M, Sweidi SA, Callier S, Di Paolo T. Estrogen and SERM neuroprotection in animal models of parkinson’s disease.Mol Cell Endocrinol. 2008;290(1):60−9.
Coelho M, Ferreira JJ. Late-stage parkinson disease. Nat Rev Neurol. 2012;8(8):435−42.
Benito-León J, Louis ED. Clinical update: diagnosis and treatment of essential tremor. The Lancet. 2007;369(9568):1152−4.
National Institute of Neurological Disorders and Stroke. Tremor fact sheet. NIH Publication; 2012:12:4734 [cited 2014 July 20]; Available from: http://www.ninds.nih.gov/disorders/tremor/detail_tremor.htm.
Jankovic J. Parkinson’s disease: clinical features and diagnosis. J Neurol Nuerosurg Psychiatry. 2008;79(4):368−76.
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